Companies founded on innovation and strong science

Arxx Therapeutics develops a first-in-class monoclonal antibody with a unique mechanism of action targeting non-resolving tissue fibrosis.

The company leverages more than 30 years of research by its scientific co-founders uncovering the pathobiology of S100A4; a Damage Associated Molecular Pattern protein upregulated upon stress or injury allowing cells to sense and react to danger. In chronically diseased tissue, S100A4 is inappropriately activated which leads to persistent inflammation and non-resolving tissue fibrosis.

Arxx’s lead candidate AX-202 is a high-affinity monoclonal antibody neutralizing the bioactivity of S100A4. AX-202 confers targeted, upstream and disease-specific modulation of the self-sustaining feedback loop driving persistent fibrogenesis.

Atai Life Sciences is a clinical-stage biopharmaceutical company that leverages a decentralized platform approach to incubate and accelerate the development of highly effective mental health treatments that address the unmet needs of patients.

It addressed the significant unmet need and lack of innovation in the mental health treatment landscape, as well as the emergence of therapies that previously may have been overlooked or underused, including psychedelic compounds and digital therapeutics.

The company aims to transform the treatment and redefine how the world approaches, prevents, and heals mental health disorders.

Rejuveron invests in subsidiary companies, co-founded with world-class scientific entrepreneurs, each focusing on one or more of the hallmarks of aging.

The company’s experienced drug discovery and development team, together with a specialist scientific advisory network, provide guidance on bringing transformative ideas into the clinic. The Rejuveron subsidiary companies share lab space, equipment, and offices, with plug-and-play access to a state-of-the-art research infrastructure.

It addressed the significant unmet need and lack of innovation in the mental health treatment landscape, as well as the emergence of therapies that previously may have been overlooked or underused, including psychedelic compounds and digital therapeutics.

The company aims to transform the treatment and redefine how the world approaches, prevents, and heals mental health disorders.

Vaccibody is a clinical-stage biopharmaceutical company dedicated to the discovery and development of novel immunotherapies for cancer, infectious diseases, and autoimmune conditions.

The company is developing cutting-edge, targeted DNA vaccines for clinical use, based on a deep understanding of immunological principles. By intelligent design, Nykode’s platform can be tailored to induce the desired immune response profile correlating with protection for each specific disease with any given antigen. Hence, the Nykode Therapeutics technology platform has the potential to address many diseases with a high unmet medical need.